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In contrast, there is no way to save the life of a Xarelto patient who has started to bleed uncontrollably. That is why Xarelto patients are discouraged from physical activities that could result in falling or internal bleeding. In addition, both Pradaxa and Xarelto can cause serious spinal cord complications, which can even cause permanent paralysis.

Both medications can also cause inflammation of the blood vessels called vasculitis , which can be minor or can cause serious problems such as blood clots, blindness, and organ damage.

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Patients taking Coumadin must also have their blood clotting monitored, to reduce their risk of bleeding. Patients can also self-monitor their blood clotting time at home using a small drop of blood from a simple finger stick.

Medicare reimburses Coumadin in full, including monitoring and requires patients to pay part of the cost for Pradaxa and Xarelto. The main advantage is convenience. Coumadin patients are required to get their blood monitored frequently to make sure the dose of Coumadin is safe. Although Pradaxa and Xarelto patients would probably also benefit from monitoring, it is not required and for that reason it is not paid for by insurance or Medicare, and not easily available.

The 75 mg dose is prescribed for patients with kidney problems and is less effective in preventing strokes than the higher dose. In other countries, a mg dose is also available and appears to offer a lower bleeding risk while still being effective. Experts have asked why the FDA did not approve the mg dose for sale in the U. Coumadin is available in several different doses which allow doctors to prescribe the dose best suited for each patient. Xarelto is prescribed in three doses that are usually taken once a day: 10 mg, 15 mg and 20 mg.

Diana Zuckerman and other senior staff. References: Coumadin prescribing information. Journal of Managed Care Pharmacy Risk of bleeding with 2 doses of dabigatran compared with warfarin in older and younger patients with atrial fibrillation:The RE-LY trial.

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  • I would be grateful if anyone could advise of costs and best places to buy the following or generic replacements In Bangkok or Hua Hin :. There are several local brands of amlodopine and it will be inexpensive.

    Available over the counter without prescription. There is only one locally made brand of atorvastatin, Chlovas, and as per post above still pretty expensive. If you can switch to simvastatin there are many local brands of that and it will save a great deal of money, suggest asking your doctor about this. Both atorvastatin and simvastatin sold over the counter without prescription. There are no local brands of dabigatran. The only brand here is Pradaxa, an expensive import. I can't tell you exact cost but it will be higher than the full retail price in the west.

    In addition, it is a "special controlled drug", requires a prescription and will usually be available only in hospitals, for which you would have to see a doctor first additional charge I suggest you either arrange to get it from your hoem country or discuss with your doctor older, alternative drugs.

    Warfarin is very cheap here and sold over the counter, though its use does require periodic blood tests. Most pharmacies stock amlodipine 5mg. Some background to my story. About 1 year ago I had a stroke. At the time of the stroke I weighed My total cholesterol has reduced to 2. I have already asked my GP about reducing the atorvastatin dose, but he was not keen on this.

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    I did not discuss changing the statin. For the atrial fibrillation I was initially taking Rivaroxoban 20mg presumably this is controlled in the same manner Sheryl? I have asked the GP about being retested for the fibrillation as it has been about 4 months since I have felt an event, but I don't always feel them anyway.

    Normally I used to pick them up when checking my blood pressure, but when I had the seven day event heart recorder test in May several were detected which I knew nothing about. Thanks again for the replies. Rivaroxoban is same story - available only as an expensive import, and requires script and usually available only from a hospital. Rivaroxoban and dabigatran are both anticoagulants. They do not treat atrial fibrillation per se, the connection is that with atrial fibrillation there is a risk of blood clots forming in the atria and breaking loose, causing stroke, heart attack or other pathology.

    Possibly this was the assumed mechanism for the stroke you had. For many years warfarin was the main drug used for this. Dabigatran, rivaroxoban and edoxaban are newer drugs and quite expensive as still under patent.

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    They are easier to take than warfarin, which requires frequent blood testing. They are also somewhat safer as warfarin has a very narrow therapeutic range easy to over "thin" the blood creating risk of bleeding , though careful regular monitoring can reduce the risks associated with warfarin. The general consensus is that these newer drugs are preferrable to warfarin where it is possible to use them - the big constraint being their high cost. Because of this high cost, in many countries the normal protocol is still to use warfarin and switch to the more expensive drug only if it proves difficult to get the desired blood parameters with warfarin.

    Pradaxa (dabigatran) mg Price Comparisons - Discounts, Cost & Coupons |

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